anti-Syndecan-1/CD138 FITC, Clone: DL-101, Invitrogen™

CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
Host Species: Mouse
Cross Reactivity: Human
Isotype: IgG1, κ
Clone: DL-101
Immunogen: Human CD138
Formulation: 100 Tests Purified Antibody (0.2mg/mL) in proprietary buffer, with 0.09% sodium azide
Synonyms: SDC1, SYND1, SDC, CD antigen 138
Uniprot Accession: P18827
Entrez GeneID: 6382
Gene Symbol: SDC1
This product detects Syndecan-1/CD138 in Human samples. This product has been successfully used in Flow Cytometry procedures. The immunogen is Human CD138.