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Invitrogen™ S100A10 Polyclonal Antibody

Código de producto. 13491437
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
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13491437 100 μL 100 microlitros
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Código de producto. 13491437 Proveedor Invitrogen™ N.º de proveedor PA527251

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Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, H1299, HeLa. Predicted reactivity: Pig (100%), Rabbit (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B (Hep B) virus polymerase. Hep B virus polymerase normally localizes to the cytoplasm only, though in the presence of S-100A10 a portion relocates to the nucleus, implying a role for S-100A10 and intracellular calcium in the process of viral replication.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno S100A10
Aplicaciones Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Clasificación Polyclonal
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
génica S100A10
N.º de referencia del gen P05943, P08207, P60903
Alias de gen 42C; AA409961; AL024248; Annexin II; annexin II ligand; annexin II ligand, calpactin I, light polypeptide; annexin II tetramer (AIIt) p11 subunit; ANX2L; ANX2LG; Ca[1]; CAL12; Cal1l; calcium binding protein A11 (calgizzarin); calpactin I light chain; Calpactin-1 light chain; cellular ligand of annexin II; CLP11; GP11; MGC111133; MGC133268; Nerve growth factor-induced protein 42C; OTTHUMP00000015270; P PRSS26; p10; p10 protein; P11; p11 subunit; Protein S100 A10; Protein S100-A10; S100 calcium binding protein A10; S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); S100 calcium binding protein A10 (calgizzarin); S100 calcium binding protein A10 (calpactin); S100 calcium-binding protein A10; S100 calcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); S-100 related protein, clone 42C; S100a10
Símbolos de los genes S100A10
Especie del huésped Rabbit
Inmunógeno Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human S100A10. The exact sequence is proprietary.
Método de purificación Antigen affinity chromatography
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 20194, 6281, 81778
Especies diana Human, Mouse, Rat
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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