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Invitrogen™ Blimp-1 Monoclonal Antibody (5E7)

Descripción
MA5-15611 targets PRDM1 in indirect ELISA, WB applications and shows reactivity with Human and mouse samples. The MA5-15611 immunogen is purified recombinant fragment of human PRDM1 expressed in E. Coli.. MA5-15611 detects PRDM1 which has a predicted molecular weight of approximately 88kDa.
Blimp-1 (B lymphocyte maturation protein-1) is a nuclear protein with five zinc fingers in its carboxy terminus. It is a transcriptional repressor that is both required and sufficient to trigger terminal differentiation of B lymphocytes and monocyte/macrophages. Blimp-1 is expressed in, and may be required for terminally differentiated epithelial cells, retinal neurons and other lineage cells. It has also been implicated in the repression of beta-interferon (IFN-beta) and c-myc gene expression.
Especificaciones
Especificaciones
| Antígeno | Blimp-1 |
| Aplicaciones | ELISA, Western Blot |
| Clasificación | Monoclonal |
| Clon | 5E7 |
| Concentración | Conc. Not Determined |
| Conjugado | Unconjugated |
| Formulación | Ascites with 0.03% sodium azide |
| génica | PRDM1 |
| N.º de referencia del gen | O75626, Q60636 |
| Alias de gen | B lymphocyte-induced maturation protein 1; b2b1765Clo; Beta-interferon gene positive regulatory domain I-binding factor; beta-interferon gene positive-regulatory domain I binding factor; BLIMP 1; Blimp1; BLIMP-1; B-lymphocyte-induced maturation protein 1; MGC118922; MGC118923; MGC118924; MGC118925; OTTHUMP00000016918; OTTHUMP00000202173; Positive regulatory domain I-binding factor 1; PR domain 1; PR domain containing 1, with ZNF domain; PR domain zinc finger protein 1; PR domain-containing protein 1; PR/SET domain 1; PRDI BF1; PRDI-BF1; PRDI-binding factor-1; Prdm1; RP1-134E15.1; ZNFPR1A1 |
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Título del producto
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