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PDI Mouse, Unlabeled, Clone: 34, BD

Mouse Monoclonal Antibody

343.00€ - 630.00€

Especificaciones

Antígeno PDI
Clon 34
Concentración 250μg/mL
Aplicaciones Western Blot
Clasificación Monoclonal
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
15875719
Ver documentos Detalles de la promoción
BD Biosciences
610946
50 μg
343.00€
1 set
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Fecha estimada de envío: 23-04-2024
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15885719
Ver documentos Detalles de la promoción
BD Biosciences
610947
150 μg
630.00€
1 set
Ver productos alternativos
Ahorre hasta 
»
Fecha estimada de envío: 23-04-2024
para ver el stock
Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Descripción

Descripción

The ER is the site of translation of membrane and secretory proteins. Following synthesis, it shuttles these proteins through a contiguous membrane system to their appropriate destinations. Protein disulfide isomerase (PDI) is an abundant, multifunctional, eukaryotic protein. Although it exhibits ubiquitous expression, it is primarily located in the ER lumen. Here, it functions to catalyze the isomerization of intramolecular disulfide bridges, thereby allowing them to generate their most thermodynamically stable configurations. This role in rearrangement has lead to the classification of PDI as a chaperone. Although protein folding occurs in its absence, PDI may be essential for it to proceed at a physiological relevant rate. In addition, PDI is the β-subunit of prolyl 4- hydroxylase and is a component of the triglyceride transfer complex. PDI is retained in the ER lumen via its C-terminal -KdaEL sequence. Via this sequence, it is continuously recycled back to the ER from other membranous compartments. Thus, PDI is a diverse protein whose primary function may be to correct disulfide bonding and, thus, ensure the most stable conformation of newly synthesized proteins.

Immunofluorescence, Western Blotting

Especificaciones

Especificaciones

PDI
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG1
Affinity Purified
34
Western Blot
Unconjugated
RUO
Canine, Human, Mouse, Rat
Bovine PDI aa. 109-214
Primary
Store undiluted at -20°C.
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Documentos

Documentos

Product Certifications

For Research Use Only.