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Munc-18 Mouse, Unlabeled, Clone: 31, BD

Mouse Monoclonal Antibody

241.00€ - 416.80€

Especificaciones

Antígeno Munc-18
Isotipo IgG1
Inmunógeno Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Formulación Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Conjugado Unconjugated
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Productos 2
Código de producto Marca Cantidad. Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad. Precio Cantidad y disponibilidad  
15825409 Ver documentos BD Biosciences
610336
50μg 241.00€
1 set Ver productos alternativos
Ahorre hasta 
»
Fecha estimada de envío
11-10-2019
Añadir a la cesta
 
15835409 Ver documentos BD Biosciences
610337
150μg 416.80€
1 set Ver productos alternativos
Ahorre hasta 
»
Fecha estimada de envío
11-10-2019
Añadir a la cesta
 
Descripción

Descripción

There are two Munc-18 isoforms: Munc-18-1 and Munc-18-2. Munc-18-1 (n-sec1 or rb-sec1; 68 kDa) is a neuronal protein that binds tightly to syntaxin 1 and functions in synaptic vesicle exocytosis. Munc-18-2 exhibits 63% amino acid sequence identity with Munc-18-1. Although Munc-18-2 is expressed in most tissues, Munc-18-1 is primarily expressed in brain. Both forms of Munc-18 bind tightly to syntaxins 1A, 2, and 3, but not to syntaxin 4. Syntaxin 1A is a plasma membrane protein implicated in synaptic vesicle docking. Following calcium entry into the presynaptic nerve terminal, the neurotransmitter-containing synaptic vesicle fuses with the plasma membrane at a region known as the active zone. Thus, by virtue of its interaction with syntaxin 1A, Munc-18-1 is thought to have an essential function in neurotransmitter release.

Especificaciones

Especificaciones

Munc-18
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Unconjugated
Cell Biology
Murine
Affinity Purified
Monoclonal
Store undiluted at -20°C.
IgG1
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Western Blot
RUO
31
250μg/mL

For Research Use Only.