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glycine cleavage system protein H (aminomethyl carrier), Mouse, Clone: 3D8-A12, Abnova™
Mouse monoclonal antibody raised against a full-length recombinant GCSH.
Marca: Abnova H00002653-M01.100ug
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Descripción
The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase; MIM 238300), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme; MIM 238310), and L protein (a lipoamide dehydrogenase; MIM 238331). Glycine encephalopathy (GCE; MIM 605899), also called nonketotic hyperglycinemia (NKH), may be due to a defect in any one of these enzymes.[supplied by OMIM
Sequence: MALRVVRSVRALLCTLRAVPLPAAPCPPRPWQLGVGAVRTLRTGPALLSVRKFTEKHEWVTTENGIGTVGISNFAQEALGDVVYCSLPEVGTKLNKQDEFGALESVKAASELYSPLSGEVTEINEALAENPGLVNKSCYEDGWLIKMTLSNPSELDELMSEEAYEKYIKSIEEEspecificaciones
| glycine cleavage system protein H (aminomethyl carrier) | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| BC000790 | |
| GCSH | |
| GCSH (AAH00790.1, 1 a.a. ∼ 173 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Yes | |
| 2653 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| IgG1 κ |
| ELISA, Western Blot | |
| 3D8-A12 | |
| Mouse monoclonal antibody raised against a full length recombinant GCSH. | |
| GCSH | |
| GCE/NKH | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Human | |
| Antibody |
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