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  6. ERK (pan ERK) Mouse, Unlabeled, Clone: 16, BD

ERK (pan ERK) Mouse, Unlabeled, Clone: 16, BD

Código de producto. p-3970598
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Cantidad:
150 μg
50 μg
Tamaño de la unidad:
1 set
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15805279 50 μg 1 set
15815279 150 μg 1 set
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Código de producto. 15805279 Proveedor BD Biosciences N.º de proveedor 610123

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Descripción

Mouse Monoclonal Antibody

The family of serine/threonine kinases known as ERKs (extracellular signal regulated kinases) or MAPKs (mitogen-activated protein kinases) are activated after cell stimulation by a variety of hormones and growth factors. Cell stimulation induces a signaling cascade that leads to phosphorylation of MEK (MAPK/ERK kinase) which, in turn, activates ERK via tyrosine and threonine phosphorylation. A myriad of proteins represent the downstream effectors for the active ERK and implicate it in the control of cell proliferation and differentiation, as well as regulation of the cytoskeleton. Activation of ERK is normally transient and cells possess dual specificity phosphatases that are responsible for its down-regulation. Furthermore, multiple studies have shown that elevated ERK activity is associated with some cancers. ERK1 may be observable migrating at 44kDa and ERK2 at 42kDa in addition to a 54kDa ERK and a MAP kinase in the 90kDa range.

Host Species: Mouse
Clone: 16
Isotype: IgG2a
Species Reactivity: Mouse
Immunogen: Rat ERK2 aa. 219-358
Formula Weight [Chemical]: 42-85kDa

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antígeno ERK (pan ERK)
Aplicaciones Western Blot
Clasificación Monoclonal
Clon 16
Concentración 250μg/mL
Conjugado Unconjugated
Descripción Extracellular signal Regulated Kinases
Formulación Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Especie del huésped Mouse
Inmunógeno Rat ERK2 aa. 219-358
Método de purificación Affinity Purified
Cantidad 50 μg
Estado normativo RUO
Disciplina de investigación Cell Biology
Primario o secundario Primary
Especies diana Canine, Chicken, Frog, Human, Mouse, Rat
Contenido y almacenamiento Store undiluted at -20°C.
Isotype IgG2a
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For Research Use Only.

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