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Disialoganglioside GD2 Mouse anti-Human, Unlabeled, Clone: 14.G2A, BD
Mouse Monoclonal Antibody
Marca: BD Biosciences 554272
249.44 EUR hasta el 2025-12-31
Use el código promocional "25339" para aplicar la oferta.
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Descripción
Gangliosides are sialic-acid bearing glycolipids that are expressed on the surface of all mammalian cells, and are likely involved in mediating cell-substratum interactions. They are important target antigens for antibody dependent cellular cytotoxicity (ADCC) of human melanoma and neuroblastoma cells. Human melanoma cells produce gangliosides, designated as GD2 and GD3 which are deposited in the subtratum-attached material, and may play a significant role in the melanoma metastatic phenotype. Clone 14.G2a specifically reacts with human and mouse GD2 ganglioside. LAN-1 human neuroblastoma cells were used as immunogen. Clone 14.G2a is an isotype switch variant selected from the parental IgG3-producing hybridoma 14.18 and has identical reactivity as the parental antibody. Clone 14.G2a is routinely tested by flow cytometry using M21 human melanoma cells.
Host Species: Mouse
Clone: 14.G2a
Isotype: IgG2a
Species Reactivity: Human
Immunogen: LAN-1 human neuroblastoma cells
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen)
Especificaciones
| Disialoganglioside GD2 | |
| Monoclonal | |
| 0.5mg/mL | |
| GD2 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C |
| Flow Cytometry | |
| 14.G2A | |
| Unconjugated | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| LAN-1 human neuroblastoma cells | |
| 0.1 mg | |
| Cell Biology | |
| Human, Mouse | |
| IgG2a |
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Título del producto
Disialoganglioside GD2 Mouse anti-Human, Unlabeled, Clone: 14.G2A, BD > 0.1mg; Unlabeled
For Research Use Only.
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