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Invitrogen™ C5AR1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA120525
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Descripción
PA1-20525 detects C5R1 in Human samples.
CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known. C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract. CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. Functionally, CD88 stimulates chemotaxis, granule enzyme release and superoxide anion production. CD88 is also a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and it may be a component of the membrane attack complex. Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.
Especificaciones
| C5AR1 | |
| Polyclonal | |
| Unconjugated | |
| C5AR1 | |
| anaphylatoxin C5a receptor; C5A; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a Receptor; C5AR; C5a-R; C5AR1; C5r1; Cd88; CD88 antigen; complement C5a receptor; complement C5a receptor 1; complement component 5 receptor 1; complement component 5, receptor 1; complement component 5a receptor 1; D7Msu1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 728 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 0.1% sodium azide | |
| P21730 | |
| C5AR1 | |
| Synthetic 18 amino acid peptide from N-terminal extracellular domain of human C5AR1/CD88. | |
| 25 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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