missing translation for 'onlineSavingsMsg'
Learn More
Learn More
CD96 Mouse anti-Human, BB515, Clone: 6F9, BD
Mouse Monoclonal Antibody
Marca: BD Biosciences 564774
Este artículo no se puede devolver.
Vea la política de devoluciones
Descripción
The 6F9 monoclonal antibody specifically binds to human CD96, also known as TACTILE (T cell activation increased late expression). CD96 is a type I transmembrane glycoprotein and member of the Ig superfamily. CD96 is expressed at low levels on resting natural killer (NK) cells and T cells and at high levels on activated NK and T cells. CD96 is also expressed on some T-cell leukemia and acute myeloid leukemia cells. CD96 may serve as a marker for acute myelogenous leukemia stem cells. CD96 plays a role in the adhesive interactions of activated NK and T cells during immune responses. CD96 binds to the poliovirus receptor (CD155) that is highly expressed by some tumor cells. CD155-mediated ligation of CD96 can induce NK cell-mediated cytotoxicity. CD96-mediated uptake of CD155 may adversely affect NK cells and thus reduce their effectiveness in anti-tumor responses.
The antibody was conjugated to BD Horizon BB515 which was developed exclusively by BD Biosciences. With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (eg, 530/30-nm filter). This dye provides a much brighter alternative to FITC with less spillover into the PE detector.
Especificaciones
| CD96 | |
| Monoclonal | |
| Brilliant Blue 515 (BB515) | |
| Aqueous buffered solution containing ≤0.09% sodium azide | |
| Human CD96 Transfected Cell Line | |
| 100 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| 6F9 | |
| TACTILE; T cell activation increased late expression | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Human | |
| IgG1 κ |
Corrección del contenido de un producto
Proporcione sus comentarios sobre el contenido del producto rellenando el siguiente formulario.
Título del producto
¿Detecta una oportunidad de mejora?Comparta una corrección de contenido