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  6. CD8 Mouse anti-Human, APC-H7, Clone: SK1, BD

CD8 Mouse anti-Human, APC-H7, Clone: SK1, BD

Product Code. p-3970150
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Cantidad:
100 Tests
25 Tests
50 Tests
Unit Size:
cada uno
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Product Code. Cantidad unitSize
15830069 25 Tests cada uno
12880500 50 Tests cada uno
15879988 100 Tests cada uno
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Product Code. 15830069 Supplier BD Biosciences Supplier No. 560273

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Description

Mouse Monoclonal Antibody

CD8 recognizes the 32kDa a-subunit of a disulfide-linked bimolecular complex. The majority of peripheral blood CD8+ T lymphocytes express an a/b heterodimer (Mr 32, 30kDa), while CD8+CD16+ natural killer (NK) lymphocytes and CD8+ T-cell receptor (TCR)-γ/δ+ lymphocytes express a/a homodimer (Mr 30kDa). CD8+TCR-α/β+ lymphocytes can express either an α/α homodimer or α/β heterodimer. The CD8 antigenic determinant binds to class I major histocompatibility (MHC) molecules resulting in increased adhesion between the CD8+ T lymphocytes and target cells. Binding of the CD8 antigen is coupled to a protein tyrosine kinase p56lck. The CD8:p56lck complex can play a role in T-lymphocyte activation through mediation of the interactions between the CD8 antigen and the CD3/TCR complex.

Host Species: Mouse
Clone: SK1
Isotype: IgG1 κ
Species Reactivity: Human
Immunogen: Human Peripheral Blood T Cells

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antígeno CD8
Aplicaciones Flow Cytometry
Clasificación Monoclonal
Clon SK1
Conjugado APC-H7
Descripción CD8α; CD8A; CD8 alpha; Leu2a; MAL; T8; p32
Formulación Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Especie del huésped Mouse
Inmunógeno Human Peripheral Blood T Cells
Método de purificación Affinity Purified
Cantidad 25 Tests
Estado normativo RUO
Disciplina de investigación Immunology
Primario o secundario Primary
Especies diana Baboon, Cynomolgus, Human, Rhesus Monkey
Contenido y almacenamiento Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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