anti-CD8 alpha RPE, Clone: OKT8, Invitrogen™

Descripción

CD8 alpha Monoclonal antibody A27083 from Invitrogen specifically detects CD8 alpha in Human samples. It is validated for Flow Cytometry.

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene.
Host Species: Mouse
Cross Reactivity: Human
Isotype: IgG2a
Clone: OKT8
Immunogen: Human CD8 alpha
Formulation: 500 Tests Purified Antibody in PBS, with 0.1% gelatin and 0.09% sodium azide
Synonyms: CD8, Leu-2, MAL, p32, CD8a
Uniprot Accession: P01732
Entrez GeneID: 925
Gene Symbol: CD8A
R-phycoerythrin (PE) is a stable and highly soluble phycobiliprotein which provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching, thus providing an exceptional quantum yields and molar extinction coefficients.