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CD42d Mouse anti-Rat, FITC, Clone: RPM.4, BD
Descripción
The RPM.4 antibody reacts with CD42d (Platelet glycoprotein V, GPV), an 88-kDa glycoprotein which noncovalently associates with GPIb and GPIX to form a receptor for von Willebrand factor on megakaryocytes and resting platelets. The binding sites for von Willebrand factor and thrombin have been localized to the GPIbα chain of the GPI-b-V-IX complex. GPV is cleaved by thrombin to release a 70 kDa soluble fragment, which contains the epitope recognized by mAb RPM.4. Although the rat CD42d protein's structure is similar to that of human CD42d, the RPM.4 antibody does not cross-react with human platelets.
Especificaciones
Especificaciones
| Antígeno | CD42d |
| Aplicaciones | Flow Cytometry |
| Clasificación | Monoclonal |
| Clon | RPM.4 |
| Concentración | 0.5mg/mL |
| Conjugado | FITC |
| Descripción | Platelet Glycoprotein V |
| Formulación | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Especie del huésped | Mouse |
| Inmunógeno | Wistar rat platelets |
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For Research Use Only.
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