anti-CD27/TNFRSF7 FITC, Clone: LG.7F9, Invitrogen™

CD27 (50 kDa) is a member of the tumor necrosis factor (TNF) receptor superfamily. CD40 and CD30 are also members of the TNF receptor superfamily. The TNF superfamily members are known for the regulation of cell proliferation and death. In contrast to the expression of other TNFR/TNF family members, expression of CD27 and its ligand CD70 is predominantly confined to lymphocytes. High expression levels of CD27 appear to be dependent on proper ligation of antigen receptors. CD70 expression requires additional co-stimulatory and/or pro-inflammatory signals. CD27 is a membranebound receptor, but a soluble form of CD27 is also produced.
Host Species: Hamster
Cross Reactivity: Human, Mouse, Rat
Isotype: IgG
Clone: LG.7F9
Immunogen: CD27 antibody was raised against mouse CD27
Formulation: 50μg Purified Antibody (0.5mg/ml) in proprietary buffer, with 0.09% sodium azide
Synonyms: CD27 antigen, CD27L receptor, T cell activation antigen CD27, T cell activation antigen S152, T-cell activation antigen CD27, tumor necrosis factor receptor superfamily member 7
Uniprot Accession: P26842, P41272
Entrez GeneID: 21940, 939
Gene Symbol: CD27
This product detects CD27/TNFRSF7 in Human, Mouse and Rat samples. This product has been successfully used in Flow Cytometry procedures. The immunogen is CD27 antibody was raised against mouse CD27.