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CD212 Mouse anti-Human, Unlabeled, Clone: 2.1E6, BD
Mouse Monoclonal Antibody
Marca: BD Biosciences 556064
Descripción
Reacts with IL-12Rβ1 subunit, one of two subunits of the IL-12Rβ. IL-12R, expressed mainly on T cells or NK cells, is a member of the hemopoietin receptor superfamily and is related to gp130, granulocyte-colony stimulating factor (G-CSF) receptor and leukemia inhibitory factor (LIF). Reports indicate that together, subunits IL-12Rβ1 and IL-12Rβ2 bind IL-12 with high affinity. IL-12 is an immunomodulatory cytokine produced mainly by antigen-presenting cells (APC) and plays a role in promoting Th1-type responses and cell-mediated immunity. It stimulates proliferation of T cells and NK cells, enhances lytic activity of lymphokine-activated killer (LAK) cells and CTL.
Especificaciones
| CD212 | |
| Monoclonal | |
| 0.5mg/mL | |
| IL-12R beta 1, IL-12 receptor β1 subunit | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C |
| Flow Cytometry | |
| 2.10E+06 | |
| Unconjugated | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| PHA-activated Human PBMC | |
| 0.1 mg | |
| Immunology | |
| Human | |
| IgG1 κ |
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For Research Use Only.