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Invitrogen™ GP130 (soluble) Monoclonal Antibody (B-T2)

Descripción
MA1-25130 detects CD130 (gp130) from human samples.
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Especificaciones
Especificaciones
| Antígeno | GP130 (soluble) |
| Aplicaciones | ELISA, Flow Cytometry |
| Clasificación | Monoclonal |
| Clon | B-T2 |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 0.09% sodium azide |
| génica | IL6ST |
| N.º de referencia del gen | P40189 |
| Alias de gen | 5133400A03Rik; AA389424; Ac1055; BB405851; CD130; CD130 antigen; CDW130; D13Ertd699e; EGK_16499; Gp130; gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form; gp130, oncostatin M receptor; GP130-RAPS; IL-6; IL-6 receptor subunit beta; IL-6R subunit beta; IL-6RB; IL-6R-beta; IL6R-beta; IL6ST; interleukin 6 signal transducer; interleukin 6 signal transducer (gp130, oncostatin M receptor); interleukin 6 signal transducer receptor; interleukin receptor beta chain; interleukin-6 receptor subunit beta; Interleukin-6 signal transducer; interleukin-6 signal transducer receptor; membrane glycoprotein; membrane glycoprotein 130; membrane glycoprotein gp130; oncostatin-M receptor subunit alpha |
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Título del producto
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