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  6. CD123 Mouse anti-Human, PerCP-Cy5.5, Clone: 7G3, BD

CD123 Mouse anti-Human, PerCP-Cy5.5, Clone: 7G3, BD

Mouse Monoclonal Antibody

143.00€ - 338.00€

Especificaciones

Antígeno CD123
Clon 7G3
Aplicaciones Flow Cytometry
Clasificación Monoclonal
Conjugado PerCP-Cyanine5.5
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Product Code Brand Cantidad Price Quantity & Availability  
15880579
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BD Biosciences
560904 		25 Tests
143.00€
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15899598
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BD Biosciences
558714 		100 Tests
338.00€
cada uno
Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Description

Description

Reacts with human CD123, the 70 kD IL-3 receptor α chain (IL-3Rα), which associates with the 120-140kDa β subunit. The β chain is shared with the receptors for interleukins IL-5 and GM-CSF. IL-3Rα is expressed on hematopoietic progenitors. This antibody has been reported to block the binding of 125I-IL-3 to high and low affinity IL-3 receptors. In functional experiments, this antibody was found to inhibit acute myeloid leukemia cell proliferation, basophil histamine release, endothelial cell-mediated IL-8 secretion, and neutrophil transmigration. This antibody has been reported to be useful for immunoprecipitation, western blot and immunofluorescent staining for flow cytometry. IL-3Rα plays an important role in hematopoietic progenitor cell growth and differentiation. At the Fifth HLDA Workshop, the human IL-3 receptor was designated CD123.

Flow Cytometry

Specifications

Specifications

CD123
Flow Cytometry
PerCP-Cyanine5.5
RUO
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
IgG2a κ
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
7G3
Monoclonal
Mouse
Human
Human IL-3Ra-transfected cells
Primary
IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha
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CD123 Mouse anti-Human, PerCP-Cy5.5, Clone: 7G3, BD

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