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CD11b Mouse anti-Rat, APC, Clone: WT.5, BD
Mouse Monoclonal Antibody
Marca: BD Biosciences 562102
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Descripción
The WT.5 monoclonal antibody specifically binds to CD11b, the α subunit of Mac-1 found on neutrophils and myeloid cells, but not on lymphocytes. Mac-1 expression is rapidly upregulated on neutrophils after activation, in the same time period that CD62L (L-selectin) is shed from the cell surface. Mac-1 mediates adhesion to ICAM-1 (CD54) and C3bi. Neutrophil binding to ICAM-1 is blocked by mAb WT.5.
Especificaciones
| CD11b | |
| Monoclonal | |
| 0.2mg/mL | |
| Itgam; Integrin αM chain; Mac-1 α chain; Integrin beta 2 alpha subunit | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Rat | |
| IgA κ |
| Flow Cytometry | |
| WT.5 | |
| APC | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Rt neutrophils | |
| 50 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |