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APEX nuclease (multifunctional DNA repair enzyme) 1 (B01), Mouse anti-Human, Polyclonal Antibody, Abnova™
Mouse polyclonal antibody raised against a full-length human APEX1 protein.
Marca: Abnova H00000328-B01
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Descripción
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq]
Sequence: MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPALYEDPPDHKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLALEspecificaciones
| APEX nuclease (multifunctional DNA repair enzyme) 1 | |
| Polyclonal | |
| Mouse polyclonal antibody raised against a full-length human APEX1 protein. | |
| APEX1 | |
| APE/APE-1/APE1/APEN/APEX/APX/HAP1/REF-1/REF1 | |
| Mouse | |
| 50 μL | |
| Transcription Regulation | |
| Primary | |
| Human | |
| Serum |
| Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot | |
| Unconjugated | |
| No additive | |
| NM_001641 | |
| APEX1 | |
| APEX1 (NP_001632, 1 a.a. ∼ 318 a.a) full-length human protein. | |
| RUO | |
| Yes | |
| 328 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
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