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Invitrogen™ AMHR2 Polyclonal Antibody
Sheep Polyclonal Antibody
Marca: Invitrogen™ PA547656
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Descripción
In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant rat MIS RII is observed, and less than 1% cross-reactivity with recombinant human TGF-beta RI, RII, RIII, and RIIB is observed. Reconstitute at 0.2 mg/mL in sterile PBS.
The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.
Especificaciones
| AMHR2 | |
| Polyclonal | |
| Unconjugated | |
| AMHR2 | |
| AMH type II receptor; AMHR; Amhr2; Anti-Muellerian hormone type II receptor; anti-Muellerian hormone type-2 receptor; anti-Mullerian hormone receptor type 11 SV1; anti-Mullerian hormone receptor type 2; anti-Mullerian hormone receptor type II; anti-Mullerian hormone receptor, type II; anti-Mullerian hormone type 2 receptor; anti-Mullerian hormone type 2 receptor delta 2; anti-Mullerian hormone type 2 receptor delta 9/10; C14; MIS type II receptor; Misiir; MISR2; MISRII; MRII; Muellerian inhibiting substance type II receptor; Mullerian inhibiting substance type II receptor | |
| Sheep | |
| Antigen affinity chromatography | |
| RUO | |
| 269 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
| ELISA, Immunohistochemistry (Paraffin), Neutralization, Western Blot | |
| 0.2 mg/mL | |
| PBS with 5% trehalose and No Preservative | |
| Q16671 | |
| AMHR2 | |
| Mouse myeloma cell line NS0-derived recombinant human MIS RII Pro18-Ser144. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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