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  6. Invitrogen™ alpha-1 Antitrypsin Monoclonal Antibody (1AT11-209.3), Invitrogen™

Invitrogen™ alpha-1 Antitrypsin Monoclonal Antibody (1AT11-209.3), Invitrogen™
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Código de producto. 11578912
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Cantidad:
1 mg
100 μg
500 μg
Tamaño de la unidad:
1 miligramo
100 microgramos
Código de producto. Cantidad unitSize
11578912 500 μg 1 miligramo
17860176 100 μg 100 microgramos
17870156 1 mg 1 miligramo
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Código de producto. 11578912

Marca: Invitrogen™ MA110627

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Descripción

Mouse Monoclonal Antibody

MA1-10627 detects alpha-1 Antitrypsin from human samples. MA1-10627 has been successfully used in ELISA applications. The MA1-10627 immunogen is purified human serum alpha-1 Antitrypsin.

Alpha-1-AT is synthesized in the liver and it acts as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung. In the absence of alpha-1-AT, these enzymes are not inhibited and they may digest pulmonary parenchyma. Alpha-1-AT deficiency is associated with chronic obstructive lung disease (emphysema) and less frequently with hepatic cirrhosis in infants and respiratory distress of the newborn. Increase in alpha-1-AT occurs as an acute phase response to tissue necrosis and inflammation. Serum level of alpha-1-AT is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis.
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Especificaciones

Antígeno alpha-1 Antitrypsin
Aplicaciones ELISA
Clasificación Monoclonal
Clon 1AT11-209.3
Concentración 0.8 mg/mL
Conjugado Unconjugated
Formulación PBS with no preservative; pH 7.4
génica SERPINA1
N.º de referencia del gen P01009
Alias de gen a-1 AT; A1A; a1-antitrypsin; A1AT; AAT; Aat2; Aat-2; alpha 1 antitrypsin; alpha-1 antitrypsin; alpha-1 protease inhibitor; Alpha-1 protease inhibitor 1; alpha-1-antiproteinase; Alpha-1-antitrypsin; alpha-1-antitrypsin (protease inhibitor); alpha-1-antitrypsin 1-1; alpha-1-antitrypsin 2; alpha-1-antitrypsin null; alpha1AT; alpha-1-protease inhibitor; alpha-1-proteinase inhibitor; Digestive Zymogen; Dom1; MGC23330; MGC9222; PI; PI1; PRO0684; PRO2209; PRO2275; protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin; protease inhibitor 1 (anti-elastase, antitrypsin, alpha-1); Protease Serine 1; serine (or cysteine) peptidase inhibitor, clade A, member 1A; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; serine (or cysteine) proteinase inhibitor, clade A (alpha-1antiproteinase, antitrypsin), member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1a; Serine Protease 1; serine protease inhibitor 1-1; Serine protease inhibitor A1a; serine protease inhibitor alpha 1; serine proteinase inhibitor, clade A, member 1; serpin A1; Serpin A1a; serpin family A member 1; serpin peptidase inhibitor clade A member 1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; SERPINA1; Serpina1a; Short peptide from AAT; SPAAT; Spi1; Spi1-1; Spi1-3; TRP1; TRY1
Símbolos de los genes SERPINA1
Especie del huésped Mouse
Inmunógeno Purified human serum alpha-1 Antitrypsin.
Método de purificación Protein A
Cantidad 500 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 5265
Especies diana Human
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Tipo de producto Antibody
Formulario Liquid
Isotype IgG1
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