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Invitrogen™ AKR1C3 Recombinant Rabbit Monoclonal Antibody (JE36-28)

Descripción
AKR1C3 Recombinant Monoclonal Antibody for Western Blot
AKR1C3 a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Especificaciones
Especificaciones
| Antígeno | AKR1C3 |
| Aplicaciones | Western Blot |
| Clasificación | Recombinant Monoclonal |
| Clon | JE36-28 |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4 |
| génica | AKR1C3 |
| N.º de referencia del gen | P42330, P51652 |
| Alias de gen | 17-beta-HSD 5; 17beta-HSD5; 17-beta-hydroxysteroid dehydrogenase type 5; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; 20-alpha-hydroxysteroid dehydrogenase; 20alpha-hydroxysteroid dehydrogenase; 2-dih; 3-alpha hydroxysteroid dehydrogenase, type II; 3-alpha-HSD type 2; 3-alpha-HSD type II, brain; 3-alpha-hydroxysteroid dehydrogenase type 2; Akr1c18; AKR1C3; Aldo-keto reductase family 1 member C18; aldo-keto reductase family 1 member C3; aldo-keto reductase family 1, member C18; aldo-keto reductase family 1, member C3; aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II); chlordecone reductase homolog HAKRb; DD3; DD-3; DDH1; DDX; Dihydrodiol dehydrogenase 3; Dihydrodiol dehydrogenase type I; dihydrodiol dehydrogenase X; HA1753; HAKRB; HAKRe; hluPGFS; HSD1; HSD17B5; Indanol dehydrogenase; KIAA0119; PGFS; prostaglandin F synthase; Testosterone 17-beta-dehydrogenase 5; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; type IIb 3-alpha hydroxysteroid dehydrogenase |
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Título del producto
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