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ADAM10 Mouse anti-Human, Clone: 2A6B7, Proteintech
Mouse Monoclonal Antibody
Marca: Proteintech 66620-1-IG-150UL
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Descripción
Proinflammatory cytokine tumor necrosis factor-a (TNF-a) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-a, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-a, notch and its ligand delta (1-3). The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively. ADAM10 mRNA is expressed in a variety of human and bovine tissues.Especificaciones
| ADAM10 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| O14672 | |
| ADAM10 | |
| ADAM10 Fusion Protein Ag23062 | |
| 150 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Western Blot | |
| 2A6B7 | |
| Unconjugated | |
| ADAM10 | |
| AD10, ADAM 10, ADAM10, CD156c, CDw156, HsT18717, kuz, Kuzbanian protein homolog, MADM | |
| Mouse | |
| Protein G | |
| RUO | |
| 102 | |
| -20°C | |
| Liquid |
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Título del producto
ADAM10 Mouse anti-Human, Clone: 2A6B7, Proteintech > 150 μL; Unconjugated
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