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Invitrogen™ ACVR2A Monoclonal Antibody (C11)
Descripción
ACVR2A Monoclonal Antibody for Western Blot, IHC (P)
Activin A receptor kinase (ACVR2A) is a type II member of the TGF-beta family of receptor Serine/Threonine kinases. ACVR2A is involved in the activin and myostatin signaling pathway. (ACVR2A Aliases: ACVR2, ACTRII). These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
Especificaciones
Especificaciones
| Antígeno | ACVR2A |
| Aplicaciones | Immunohistochemistry (Paraffin), Western Blot |
| Clasificación | Monoclonal |
| Clon | C11 |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 |
| génica | ACVR2A |
| N.º de referencia del gen | P27037 |
| Alias de gen | activin A receptor type 2A; activin A receptor type IIA; activin A receptor, type IIA; activin receptor IIA; activin receptor type IIA; Activin receptor type-2A; Actrii; ActrIIa; ACTR-IIA; ACVR2; Acvr2a; rActR-II; TactrII; type II activin receptor |
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Título del producto
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