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Invitrogen™ ABCG5 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA578701
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Descripción
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: MCF-7 whole cell, A549 whole cell, HT1080 whole cell, U87 whole cell, SKOV whole cell. Flow: A431 cell.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.
Especificaciones
| ABCG5 | |
| Polyclonal | |
| Unconjugated | |
| ABCG5 | |
| Abcg5; ATP binding cassette subfamily G member 5; ATP-binding cassette sub-family G (WHITE) member 5 (sterolin 1); ATP-binding cassette sub-family G member 5; ATP-binding cassette, subfamily G (WHITE), member 5; ATP-binding cassette, sub-family G (WHITE), member 5; ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1); ATP-binding cassette, subfamily G, member 5; AW112016; cmp; sterolin 1; sterolin-1; STSL; trac | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 64240 | |
| -20°C | |
| Lyophilized |
| Flow Cytometry, Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry | |
| 500 μg/mL | |
| PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal | |
| Q9H222 | |
| ABCG5 | |
| A synthetic peptide corresponding to a sequence at the N-terminus of human ABCG5 (116-131aa NGRALRREQFQDCFSY). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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