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53BP2 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 26550-1-AP-20UL
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Descripción
Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.Especificaciones
| 53BP2 | |
| Polyclonal | |
| Unconjugated | |
| TP53BP2 | |
| 53BP2, ASPP2, BBP, p53 binding protein 2, p53BP2, PPP1R13A, TP53BP2 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 7159 | |
| -20°C | |
| Liquid |
| Western Blot | |
| 0.3 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q13625 | |
| TP53BP2 | |
| 53BP2 Fusion Protein Ag24907 | |
| 20 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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