missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Descripción
Immunogen sequence: PQPSKDTLLP PFRKPQTVAA SSIYSMYTQQ QAPGKNFQQA VQSALTKTHT RGPHFSSVYG KPVIAAAQNQ QQHPENIYSN SQGKPGSPEP ETEPVSSVQE NHENERI Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 90%.
Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.
Especificaciones
Especificaciones
| Antígeno | 53BP2 |
| Aplicaciones | Immunohistochemistry (Paraffin), Immunocytochemistry |
| Clasificación | Polyclonal |
| Concentración | 0.1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| génica | TP53BP2 |
| N.º de referencia del gen | Q13625 |
| Alias de gen | 53BP2; Apoptosis-stimulating of p53 protein 2; apoptosis-stimulating protein of p53, 2; ASPP2; BBP; Bcl2-binding protein; P PPP1R13A; P53BP2; PPP1R13A; Renal carcinoma antigen NY-REN-51; TP53BP2; transformation related protein 53 binding protein 2; Trp53bp2; tumor protein p53 binding protein 2; tumor protein p53 binding protein, 2; tumor suppressor p53-binding protein 2 |
| Símbolos de los genes | TP53BP2 |
| Mostrar más |
Título del producto
Al hacer clic en Enviar, acepta que Fisher Scientific se ponga en contacto con usted en relación con los comentarios que ha proporcionado en este formulario. No compartiremos su información para ningún otro fin. Toda la información de contacto proporcionada se mantendrá de acuerdo con nuestra Política de Privacidad. Política de privacidad.
¿Detecta una oportunidad de mejora?
