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  6. TdB Labs AB 500 kDa FITC-dextran Sulfate Green Fluorophore

TdB Labs AB 500 kDa FITC-dextran Sulfate Green Fluorophore

Código de producto. 30216252
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Cantidad:
100 mg
1 g
Tamaño de la unidad:
1 g
100 miligramos
Código de producto. Cantidad unitSize
30216252 100 mg 100 miligramos
30216521 1 g 1 g
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Código de producto. 30216252

Marca: TdB Labs AB FDSS500_100mg

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Descripción

FITC-dextran sulfate 500 kDa is a green-fluorescent, highly sulfated macromolecule used in virus binding, electrostatic interaction studies, and macromolecular transport assays where strong negative charge is required.

  • Product Overview: FITC-dextran sulfates are highly sulfated dextran molecules covalently labeled with fluorescein isothiocyanate (FITC), combining strong negative charge with bright green fluorescence. Available in 4 kDa, 10 kDa, 40 kDa, and 500 kDa molecular weights, FITC-dextran Sulfates are ideal for permeability studies, barrier function assays, and molecular interaction research where anionic tracers are required.
  • Features:
    • Green Fluorescence: Excitation maximum at 495 nm and emission maximum at 519 nm, compatible with standard FITC filter sets.
    • Highly Sulfated Structure: Provides strong negative charge density, mimicking the behavior of naturally occurring polyanions like heparin.
    • Wide Molecular Weight Range: Offered at 4 kDa, 10 kDa, 40 kDa, and 500 kDa to match different permeability and diffusion model requirements.
    • Water-Soluble: Fully soluble in aqueous media, facilitating easy preparation for biological and analytical experiments.
    • Controlled Labeling and Consistency: Manufactured under strict specifications to ensure reproducible fluorescence intensity and sulfation degree across batches.
  • Benefits:
    • Reliable Permeability Probes: Ideal for studying transport properties across biological membranes, vascular barriers, and engineered tissues.
    • Electrostatic Interaction Research: Useful for investigating binding to cationic proteins, peptides, or biomaterials.
    • Modeling Charged Molecule Behavior: Acts as an analog for anionic macromolecules in studies of transport, adsorption, and separation.
    • Flexible Application Across Systems: Suitable for live-cell, tissue culture, microfluidics, and in vivo tracer studies.
    • Bright and Stable Fluorescence: Enables sensitive detection and quantitative analysis using fluorescence-based methods.
  • Applications:
    • Barrier Function Assays: Used to assess the integrity of epithelial and endothelial monolayers, including gut and blood-brain barrier models.
    • Vascular Permeability Studies: Applied to measure vascular leakiness under physiological and pathological conditions.
    • Charge-Dependent Binding Studies: Investigates interactions between anionic molecules and cationic surfaces or proteins.
    • Tracer Studies in Microfluidics and Perfusion Systems: Tracks the movement of charged molecules through engineered or natural channels.
    • Cell Culture and Tissue Engineering Models: Maps molecular diffusion and barrier formation in tissue constructs and organoids.
  • Technical Specifications:
    • Fluorescence: Excitation maximum at 495 nm, emission maximum at 519 nm.
    • Molecular Weights: 4 kDa, 10 kDa, 40 kDa, and 500 kDa.
    • Appearance: Light-sensitive, greenish dry powder, readily soluble in water.
    • Sulfation Level: High, typically 16 to 20% sulfur content, depending on grade.
  • Storage and Stability:
    • Store dry, protected from light, at 2°C to 8°C for maximum stability and fluorescence preservation.
    • Stable under recommended conditions for long-term storage and experimental reliability.
  • Packaging and Availability:
    • Supplied as dry powder, facilitating long shelf life and ease of storage.
    • Available in various pack sizes to support both small-scale experiments and larger research projects.

Especificaciones

Cantidad 100 mg
Tipo de producto Fluorescent Labeling Reagent
Peso molecular 500 kDa
Tipo de etiqueta Other Labels or Dyes
Color Green
Título del producto
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