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Invitrogen™ IRAK-M Recombinant Rabbit Monoclonal Antibody (23GB875), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Marca: Invitrogen™ MA554018
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Descripción
IRAK3 serine/threonine kinase or interleukin-1 receptor-associated kinase 3 is a member of the interleukin-1 receptor-associated kinase protein family which are essential components of the Toll/IL-R immune signal transduction pathways. IRAK3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. IRAK3 mediates critical aspects of innate immunity that result in an immunocompromised state during sepsis. Mutations in IRAK3 are associated with a susceptibility to asthma.
Especificaciones
| IRAK-M | |
| Recombinant Monoclonal | |
| Unconjugated | |
| IRAK3 | |
| 4833428C18Rik; AI563835; ASRT5; FLJ13601; IL-1 receptor-associated kinase M; interleukin 1 receptor associated kinase 3; interleukin-1 receptor-associated kinase 3; IRAK3; IRAK-3; IRAKM; IRAK-M | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 11213 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 23GB875 | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q9Y616 | |
| IRAK3 | |
| A synthetic peptide of human IRAK3 (550-596AA). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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