CAS RN 298690-60-5
IUPAC Nombre:
2-(4-fluorophenyl)-1-(4-methylbenzenesulfonyl)pyrrolidine
Sinónimos:
2-(4-fluorophenyl)-1-(4-methylbenzenesulfonyl)pyrrolidine
Peso molecular (g/mol):
319.39
Fórmula molecular:
C17H18FNO2S
InChi Key:
DAEHFYNGSSBGSS-UHFFFAOYNA-N
SMILES:
CC1=CC=C(C=C1)S(=O)(=O)N1CCCC1C1=CC=C(F)C=C1
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Tocris Bioscience™ Ro 67-7476
CAS: 298690-60-5 Fórmula molecular: C17H18FNO2S
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Ro 67-7476, MedChemExpress
MedChemExpress Ro 67-7476 is a potent positive allosteric modulator of mGluR1 and potentiates glutamate-induced calcium release in HEK293 cells expressing rat mGluR1a with an EC50 of 60.1 nM. Ro 67-7476 is a potent P-ERK1/2 agonist and activates ERK1/2 phosphorylation in the absence of exogenously added glutamate (EC50=163.3 nM).
