CAS RN 1346547-00-9
IUPAC Nombre:
N-(5-fluoro-1H-indazol-3-yl)-6-(2-methylpropane-2-sulfonyl)quinolin-4-amine
Sinónimos:
N-(5-fluoro-1H-indazol-3-yl)-6-(2-methylpropane-2-sulfonyl)quinolin-4-amine
Peso molecular (g/mol):
398.46
Fórmula molecular:
C20H19FN4O2S
InChi Key:
XLOGLWKOHPIJLV-UHFFFAOYSA-N
SMILES:
CC(C)(C)S(=O)(=O)C1=CC=C2N=CC=C(NC3=NNC4=CC=C(F)C=C34)C2=C1
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Tocris Bioscience™ GSK 583
Potent RIP2 kinase inhibitor; orally bioavailable and cell permeable
3
GSK583, MedChemExpress
MedChemExpress GSK583 is a highly potent, orally active and selective inhibitor of RIP2 Kinase, with IC50 of 5 nM. GSK583 inhibits both TNF-α and IL-6 production with an IC50 value of 200 nM.
