CAS RN 755037-03-7

1 – 2 de 2 resultados

Regorafenib, TRC

CAS: 755037-03-7 Fórmula molecular: C21 H15 Cl F4 N4 O3 Peso molecular (g/mol): 482.82 Sinónimo: 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-,4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide,4-[4-[N'-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic acid methylamide,BAY 73-4506,Regorafenib,Stivarga Nombre IUPAC: 4-[4-[[4-cloro-3-(trifluorometil)fenil]carbamoilamino]-3-fluorofenoxi]-N-metilpiridina-2-carboxamida SMILES: CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)ccn1

Precio y disponibilidad
Especificaciones

Sinónimo	2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-,4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide,4-[4-[N'-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic acid methylamide,BAY 73-4506,Regorafenib,Stivarga
Fórmula molecular	C21 H15 Cl F4 N4 O3
CAS	755037-03-7
Peso molecular (g/mol)	482.82
SMILES	CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)ccn1
Nombre IUPAC	4-[4-[[4-cloro-3-(trifluorometil)fenil]carbamoilamino]-3-fluorofenoxi]-N-metilpiridina-2-carboxamida

Regorafenib, MedChemExpress

MedChemExpress Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Regorafenib shows very robust antitumor and antiangiogenic activity.

Precio y disponibilidad
Especificaciones

Sinónimo	BAY 73-4506
Información de solubilidad	DMSO : 150 mg/mL (310.67 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
Forma física	Solid
Almacenamiento recomendado	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Color	Blanco
SMILES	O=C(NC1=CC=C(C(C(F)(F)F)=C1)Cl)NC2=CC=C(OC3=CC(C(NC)=O)=NC=C3)C=C2F
Notas de grado de pureza	Research
Duración de almacenamiento	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formula Weight (peso de la fórmula)	482.82
Fórmula molecular	C₂₁H₁₅ClF₄N₄O₃
CAS	755037-03-7
Nombre del producto químico o material	Regorafenib
Porcentaje de pureza	98.99%
Peso molecular (g/mol)	482.82
Grado	Research
Para utilizar con (aplicación)	Cancer-Kinase/protease

Resultados de la búsqueda filtrada

Limitar resultados