CAS RN 524684-52-4
IUPAC Nombre:
4-[(2Z)-7-ethenyl-5-hydroxy-2,3-dihydro-1,3-benzoxazol-2-ylidene]-2-fluorocyclohexa-2,5-dien-1-one
Sinónimos:
prinaberel
Peso molecular (g/mol):
271.25
Fórmula molecular:
C15H10FNO3
InChi Key:
FCXYSEXZEGPLGG-DHDCSXOGSA-N
SMILES:
OC1=CC2=C(O\C(N2)=C2\C=CC(=O)C(F)=C2)C(C=C)=C1
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resultados
1
Tocris Bioscience™ ERB 041
CAS: 524684-52-4 Fórmula molecular: C15H10FNO3
2
Prinaberel, MedChemExpress
MedChemExpress Prinaberel (ERB-041) is a potent and selective estrogen receptor (ER) β agonist with IC50s of 5.4, 3.1 and 3.7 nM for human, rat and mouse ERβ, respectively. Prinaberel displays >200-fold selectivity for ERβ over ERα. Prinaberel is a potent skin cancer chemopreventive agent that acts by dampening the WNT/β-catenin signaling pathway. Prinaberel induces ovarian cancer apoptosis.
