CAS RN 443797-96-4
IUPAC Nombre:
4-{[5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino}benzene-1-sulfonamide
Sinónimos:
4-{[5-amino-1-(2,6-difluorobenzoyl)-1,2,4-triazol-3-yl]amino}benzenesulfonamide
Peso molecular (g/mol):
394.36
Fórmula molecular:
C15H12F2N6O3S
InChi Key:
KDKUVYLMPJIGKA-UHFFFAOYSA-N
SMILES:
NC1=NC(NC2=CC=C(C=C2)S(N)(=O)=O)=NN1C(=O)C1=C(F)C=CC=C1F
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JNJ-7706621, MedChemExpress
MedChemExpress JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2, with IC50s of 9 nM, 3 nM, 11 nM, and 15 nM for CDK1, CDK2, aurora-A and aurora-B, respectively.
