CAS RN 423148-78-1
IUPAC Nombre:
1-(3-chloro-4-fluorophenyl)-4-[(5-nitrofuran-2-yl)methylidene]pyrazolidine-3,5-dione
Sinónimos:
1-(3-chloro-4-fluorophenyl)-4-[(5-nitrofuran-2-yl)methylidene]pyrazolidine-3,5-dione
Peso molecular (g/mol):
351.67
Fórmula molecular:
C14H7ClFN3O5
InChi Key:
MSYMKEYWUWVZQY-UHFFFAOYSA-N
SMILES:
[O-][N+](=O)C1=CC=C(O1)C=C1C(=O)NN(C1=O)C1=CC(Cl)=C(F)C=C1
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PYZD-4409, MedChemExpress
MedChemExpress PYZD-4409 is a specific inhibitor of the ubiquitin-activating enzyme UBA1 with an IC50 of 20 μM (cell-free enzymatic assay). PYZD-4409 induces cell death in malignant cells and preferentially inhibits the clonogenic growth of primary acute myeloid leukemia cells.
