CAS RN 1221349-53-6
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Tocris Bioscience™ TC-I 2014
Potent TRPM8 antagonist
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TC-I 2014, MedChemExpress
MedChemExpress TC-I 2014 (compound 5) is a potent and orally active Benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonist, with IC50 values of 0.8 nM, 3.0 nM and 4.4 nM for canine, human and rat channels respectively. TC-I 2014 exhibits antiallodynic properties in pain models.
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