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  6. 18798446

WIKI4

Potent tankyrase inhibitor

Brand:  Tocris Bioscience 4855/25

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Product Code. 18798446

  • 651.00€ / 25mg

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Description

Description

WIKI4 is an inhibitor of Wnt/β-catenin signaling (EC50 ∼ 75 nM). Inhibits auto-ADP-ribosylation of tankyrase 2 (TNKS2) (IC50 ∼15 nM); prevents the ubiquitination and degradation of axin. WIKI4 inhibits expression of β-catenin target genes in cancer cell lines as well as in human embryonic stem cells (ESC).

WIKI4 synthesized to Ancillary Material Grade also available.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

2-[3-[[4-(4-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]-1H-benz[de]isoquinoline-1,3(2H)-dione
>98%
C29H23N5O3S
838818-26-1
25 mg
Observed MW: 521.59
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