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  6. Transglutaminase 2/TGM2 Antibody (TGM2/419), R&D Systems™

Transglutaminase 2/TGM2 Antibody (TGM2/419), R&D Systems™

Código de producto. 18600856 Tienda Bio Techne Productos
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0.02 mg
0.1 mg
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0.10 miligramo
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18600856 0.1 mg 0.10 miligramo
18121029 0.02 mg 0.02 miligramo
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Código de producto. 18600856 Proveedor Novus Biologicals N.º de proveedor NBP2445940.1mg
  • ONLINE EXCLUSIVE PRICE
    568.05€
    483.00€ / 0.1 miligramos
    Ahorro 85.05€
    14% Descuento
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Fecha estimada de envoi: 26-11-2026
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Descripción

A Novus product, part of R&D Systems. Mouse Monoclonal Antibody

Transglutaminase 2/TGM2 Monoclonal specifically detects Transglutaminase 2/TGM2 in Human, Monkey, Mouse, Rabbit, Rat samples. It is validated for Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno Transglutaminase 2/TGM2
Aplicaciones Immunohistochemistry, Western Blot
Clasificación Monoclonal
Clon TGM2/419
Concentración 0.2mg/mL
Conjugado Unconjugated
Dilución Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Formulación 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
N.º de referencia del gen P21980
Alias de gen C polypeptide, EC 2.3.2.13, G-ALPHA-h, protein-glutamine gamma-glutamyltransferase 2, protein-glutamine-gamma-glutamyltransferase, TG(C), TG2, TGase C, TGase H, TGase-2, TGase-H, TGCGNAH, Tissue transglutaminase, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase), Transglutaminase C, Transglutaminase H, Transglutaminase-2
Símbolos de los genes TGM2
Especie del huésped Mouse
Inmunógeno Recombinant full-length human TGM2 protein
Método de purificación Protein A or G purified
Cantidad 0.1 mg
Estado normativo RUO
Disciplina de investigación Apoptosis, Immune System Diseases, Immunology, Signal Transduction
Primario o secundario Primary
ID de gen (Entrez) 7052
Especificidad de la prueba Recognizes a 77-85kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
Especies diana Human, Monkey, Mouse, Rabbit, Rat
Contenido y almacenamiento Store at 4C.
Formulario Purified
Isotype IgG2a κ
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For Research Use Only

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