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Thiamphenicol

Código de producto. 15495769
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25 g
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Código de producto. 15495769 Proveedor Thermo Scientific Alfa Aesar N.º de proveedor J63575.06
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Descripción

The methyl-sulfonyl analogue of chloramphenicol | CAS: 15318-45-3 | C12H15Cl2NO5S | 356.214 g/mol

Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

Solubility
Soluble in acetonitrile or DMF. Slightly soluble in water

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
TRUSTED_SUSTAINABILITY

Identificadores de productos químicos

CAS 15318-45-3
Fórmula molecular C12H15Cl2NO5S
Peso molecular (g/mol) 356.214
Número MDL MFCD00467983
Clave InChI OTVAEFIXJLOWRX-NXEZZACHSA-N
Sinónimo thiamphenicol, thiophenicol, thiamcol, +-thiamphenicol, raceophenidol, thiocymetin, dextrosulphenidol, thiamphenicolum, d-thiocymetin, d-thiophenicol
PubChem CID 27200
ChEBI CHEBI:32215
Nombre IUPAC 2,2-dicloro-N-[(1R,2R)-1,3-dihidroxi-1-(4-metilsulfonilfenil)propan-2-il]acetamida
SMILES CS(=O)(=O)C1=CC=C(C=C1)C(C(CO)NC(=O)C(Cl)Cl)O

Especificaciones

Nombre del producto químico o material Thiamphenicol
Color Blanco a amarillo
Cantidad 5 g
Beilstein 2819542
Índice Merck 14,9301
Información de solubilidad Soluble in acetonitrile or DMF; Slightly soluble in water
Formula Weight (peso de la fórmula) 356.22
Forma física Powder

RUO – Research Use Only

Título del producto
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