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Gibco™ PeproGMP® Human VEGF-165 Recombinant Protein, PeproTech®

Código de producto. 30275722
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Cantidad:
100 μg
1 mg
50 μg
Tamaño de la unidad:
1 miligramo
100 microgramos
50 microgramos
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Código de producto. Cantidad unitSize
30275722 1 mg 1 miligramo
30275491 100 μg 100 microgramos
30275000 50 μg 50 microgramos
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Código de producto. 30275722 Proveedor Gibco™ N.º de proveedor GMP100201MG

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Descripción

Recombinant Protein

Recombinant Human VEGF 165 is a 38.2 kDa, disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains. Additional product information and specifications are provided on the Certificate of Analysis. All PeproGMP® products are manufactured using animal-derived component free materials. Product Description/Intended Use: PeproTech GMP recombinant proteins are manufactured for use as ancillary materials by applying applicable principles of GMP and quality control requirements from USP (United States Pharmacopeia) Chapter 1043 Ancillary Materials for Cell, Gene, and Tissue-Engineered Products. Product use statement: For research use or further manufacturing. Not for diagnostic use or direct administration into humans or animals.

The vascular endothelial growth factor (VEGF) family currently includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis. Most tumors have the absolute requirement of angiogenesis and VEGF has been described as the most potent angiogenic cytokine linked to this process. To date 5 different isoforms of VEGF have been described. These isoforms are generated as the result of alternative splicing from a single VEGF gene. These various isoforms have been shown to bind to two tyrosine-kinase receptors flt-1 (VEGFR-1) and flk-1/KDR (VEGFR-2), which have been found to be expressed almost exclusively on endothelial cells.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso P15692
Para utilizar con (aplicación) Control, Western Blot Control, Bioactivity
Formato Lyophilized
Formulación Protein with no preservative
ID de gen (Entrez) 7422
Peso molecular 38.2 kDa
Nombre PeproGMP™ Human VEGF-165
Método de purificación Purified
Cantidad 1 mg
Requisitos de almacenamiento -20°C or -80°C if preferred
Estado normativo GMP
Concentración de endotoxinas ≤0.1 EU/μg
Alias de gen H-VEGF-165; MVCD1; M-VEGF-165; vascular endothelial growth factor 165b; vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular permeability factor; VEGF; VEGF164; VEGF165; Vegfa; VEGF-A; VPF
Nombre común VEGF-165
Símbolo de gen Vegfa
Actividad biológica Determined by the proliferation of HUVECs.
Tipo de producto Protein
Conjugado Unconjugated
Recombinante Recombinant
Secuencia APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
Contenido y almacenamiento -20°Cor to +80°C if preferred
Actividad Determined by the proliferation of HUVECs.
Sistema de expresión E. coli
Formulario Lyophilized
Línea de productos PeproGMP
Grado de pureza o calidad ≥ 98% by SDS-PAGE gel and HPLC analyses.
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