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Gibco™ PeproGMP® Human IL-3 Recombinant Protein, PeproTech®

Código de producto. 30276693
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Cantidad:
100 μg
1 mg
50 μg
Tamaño de la unidad:
1 miligramo
100 microgramos
50 microgramos
Código de producto. Cantidad unitSize
30276693 1 mg 1 miligramo
30275259 100 μg 100 microgramos
30275260 50 μg 50 microgramos
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Código de producto. 30276693

Marca: Gibco™ GMP200031MG

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Descripción

Recombinant Protein

Additional product information and specifications are provided on the Certificate of Analysis. All PeproGMP® products are manufactured using animal-derived component free materials. Product Description/Intended Use: PeproTech GMP recombinant proteins are manufactured for use as ancillary materials by applying applicable principles of GMP and quality control requirements from USP (United States Pharmacopeia) Chapter 1043 Ancillary Materials for Cell, Gene, and Tissue-Engineered Products. Product use statement: For research use or further manufacturing. Not for diagnostic use or direct administration into humans or animals.

Interleukin 3 (IL-3), also called Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells and eosinophils. IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell and monocytic lineages. Most of these functions are enhanced or dependent on co-stimulation with other cytokines. Human and mouse IL-3 share only 29% sequence identity at the amino acid level. The bioactivity of IL-3 is highly species specific. For example, human IL-3 has no activity on mouse cells. IL-3 is a potent growth promoting cytokine. IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types, and is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso P08700
Para utilizar con (aplicación) Control, Western Blot Control, Bioactivity
Formato Lyophilized
Formulación Protein with no preservative
ID de gen (Entrez) 3562
Peso molecular 15 kDa
Nombre PeproGMP™ Human IL-3
Método de purificación Purified
Cantidad 1 mg
Requisitos de almacenamiento -20°C or -80°C if preferred
Estado normativo GMP
Concentración de endotoxinas ≤0.1 EU/μg
Alias de gen BP/BPA; BPA; Colony stimulating factor multiple; colony-stimulating factor, multiple; Csfmu; Eo-CSF; HCGF; hematopoietic growth factor; Il3; Il-3; ILN; Interleukin; interleukin 3; Interleukin 3 (colony stimulating factor; Interleukin3; interleukin-3; Mast cell growth factor; mast-cell growth factor; MCGF; MGC79398; MGC79399; MGF; Multi CSF; MULTI-CSF; Multilineage colony stimulating factor; multilineage-colony-stimulating factor; multiple); multipotential colony-stimulating factor; P cell stimulating factor; P-cell stimulating factor; P-cell-stimulating factor; PCSA; PSF
Nombre común IL-3
Símbolo de gen IL3
Actividad biológica Determined by the proliferation of TF-1 cells. PeproGMP Recombinant Human IL-3 ha been tested against the WHO standard NIBSC 91/510.
Tipo de producto Protein
Conjugado Unconjugated
Recombinante Recombinant
Secuencia APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF
Contenido y almacenamiento -20°Cor to +80°C if preferred
Actividad Determined by the proliferation of TF-1 cells. PeproGMP Recombinant Human IL-3 has been tested against the WHO standard NIBSC 91/510. Find the International Unit (IU) value <a href='https://www.thermofisher.com/us/en/home/life-science/cell-culture/cell-culture-learning-center/recombinant-protein-information/international-units.html'>here</a>.
Sistema de expresión E. coli
Formulario Lyophilized
Línea de productos PeproGMP
Grado de pureza o calidad ≥ 98% by SDS-PAGE gel and HPLC analyses.
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