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Gibco™ PeproGMP® Human Heregulin beta-1 Recombinant Protein, PeproTech®

Código de producto. 30275004
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Cantidad:
100 μg
1 mg
50 μg
Tamaño de la unidad:
1 miligramo
100 microgramos
50 microgramos
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Código de producto. Cantidad unitSize
30275004 1 mg 1 miligramo
30276207 100 μg 100 microgramos
30276691 50 μg 50 microgramos
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Código de producto. 30275004 Proveedor Gibco™ N.º de proveedor GMP100031MG

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Recombinant Protein

Additional product information and specifications are provided on the Certificate of Analysis. All PeproGMP® products are manufactured using animal-derived component free materials. Product Description/Intended Use: PeproTech GMP recombinant proteins are manufactured for use as ancillary materials by applying applicable principles of GMP and quality control requirements from USP (United States Pharmacopeia) Chapter 1043 Ancillary Materials for Cell, Gene, and Tissue-Engineered Products. Product use statement: For research use or further manufacturing. Not for diagnostic use or direct administration into humans or animals.

Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso Q02297
Para utilizar con (aplicación) Control, Western Blot Control, Bioactivity
Formato Lyophilized
Formulación Protein with no preservative
ID de gen (Entrez) 3084
Peso molecular 7.5 kDa
Nombre PeproGMP™ Human Heregulin beta-1
Método de purificación Purified
Cantidad 1 mg
Requisitos de almacenamiento -20°C or -80°C if preferred
Estado normativo GMP
Concentración de endotoxinas ≤0.1 EU/μg
Alias de gen 6030402G23Rik; acetylcholine receptor-inducing activity; ARIA; Breast cancer cell differentiation factor p45; D230005F13Rik; GGF; GGF2; GGFII; Glial growth factor; glial growth factor 2; heregulin; heregulin, alpha (45kD, ERBB2 p185-activator); Hgl; HRG; HRG1; HRGA; HRGalpha; MST131; MSTP131; NDF; Neu differentiation factor; neuregulin 1; neuregulin 1 type III beta 3; Neuregulin-1; Nrg1; NRG1-IT2; Pro-neuregulin-1, membrane-bound isoform; pro-NRG1; sensory and motor neuron derived factor; Sensory and motor neuron-derived factor; SMDF; type I neuregulin 1; type III neuregulin 1
Nombre común HRG beta-1
Símbolo de gen Nrg1
Actividad biológica Determined by proliferation of human MCF-7 cells.
Tipo de producto Protein
Conjugado Unconjugated
Recombinante Recombinant
Secuencia SHLVKCAEKE KTFCVNGGEC FMVKDLSNPS RYLCKCPNEF TGDRCQNYVM ASFYKHLGIE FMEAE
Contenido y almacenamiento -20°Cor to +80°C if preferred
Actividad Determined by proliferation of human MCF-7 cells.
Sistema de expresión E. coli
Formulario Lyophilized
Línea de productos PeproGMP
Grado de pureza o calidad ≥ 98% by SDS-PAGE gel and HPLC analyses.
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