Gibco™ PeproGMP™ Human BMP-4 Recombinant Protein, PeproTech®

Recombinant Protein

Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-beta superfamily of structurally related signaling proteins. PeproTech's E. coli-derived Human BMP-4 is a fully active homodimeric protein consisting of two 107 amino acid subunits, which correspond to amino acids 303-408 of the full-length BMP-4 precursor, as well as an N-terminal methionine. PeproTech Recombinant Human BMP-4 is a 24.2 kDa protein. PeproGMP BMP-4 can be used with PeproGMP VEGF-165 and PeproGMP SCF in CTS StemScale medium for pluripotent stem cell differentiation, specifically for mesoderm and hematopoetic progenitor cell induction. Reconstitute using 5mM HCl, pH 3.0 to a concentration of 0.1-1.0 mg/ml. Additional product information, specifications, handling and reconstitution information are provided on the Certificate of Analysis. All PeproGMP™ products are manufactured using animal-derived component free materials. Product Description/Intended Use: PeproTech GMP recombinant proteins are manufactured for use as ancillary materials by applying applicable principles of GMP and quality control requirements from USP (United States Pharmacopeia) Chapter <1043> Ancillary Materials for Cell, Gene, and Tissue-Engineered Products.