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Pamapimod, MedChemExpress

Código de producto. 16433948
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Código de producto. 16433948 Proveedor Medchem Express N.º de proveedor HY10405

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Descripción

MedChemExpress Pamapimod (Ro4402257) is a potent, selective and orally active p38 MAPK inhibitor with IC50s of 14 nM and 480 nM and Kis of 1.3 nM and 120 nM for p38α and p38β, respectively. Pamapimod has no activity against p38δ or p38γ isoforms. Pamapimod has the potential for rheumatoid arthritis and other autoimmune diseases treatment.

Pamapimod (Ro4402257) is a potent, selective and orally active p38 MAPK inhibitor with IC50s of 14 nM and 480 nM and Kis of 1.3 nM and 120 nM for p38α and p38β, respectively. Pamapimod has no activity against p38δ or p38γ isoforms. Pamapimod has the potential for rheumatoid arthritis and other autoimmune diseases treatment.

Especificaciones

Nombre del producto químico o material Pamapimod
CAS 449811-01-2
Color Off-White
Notas de grado de pureza Research
Fórmula molecular C19H20F2N4O4
Cantidad 10 mg
Sinónimo Ro4402257 R1503
Información de solubilidad DMSO : ≥ 34 mg/mL (83.67 mM)
SMILES O=C1C(OC2=CC=C(F)C=C2F)=CC3=CN=C(NC(CCO)CCO)N=C3N1C
Peso molecular (g/mol) 406.38
Formula Weight (peso de la fórmula) 406.38
Porcentaje de pureza 99.92%
Grado Research
Forma física Powder
Para utilizar con (aplicación) Cancer-Kinase/protease
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Research purposes only

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