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Invitrogen™ Human NTRK3 (TRKC), His Tag Recombinant Protein

Código de producto. 11513477
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Cantidad:
10 μg
1 mg
Tamaño de la unidad:
1 miligramo
10 microgramos
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11513477 10 μg 10 microgramos
10185772 1 mg 1 miligramo
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Código de producto. 11513477 Proveedor Invitrogen™ N.º de proveedor PV3617

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Descripción

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Catalytic Domain, Cytoplasmic.

NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso Q16288
Concentración See Label
Para utilizar con (aplicación) Kinase Assay
Formulación 50mM tris HCl with 0.05% Triton X-100, 50% glycerol, 4mM DTT, 150mM NaCl, 0.5mM EDTA and no preservative; pH 7.5
ID de gen (Entrez) 4916
Peso molecular 41.2 kDa
Nombre Human NTRK3 (TRKC), His Tag
Intervalo de pH 7.5
Método de purificación Purified
Cantidad 10 μg
Requisitos de almacenamiento -80°C, Avoid Freeze/Thaw Cycles
Estado normativo RUO
Alias de gen AW125844; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); GP145-TrkC; neural receptor protein-tyrosine kinase (trkC); neurotrophic receptor tyrosine kinase 3; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 3; neurotrophin-3; NT-3 growth factor receptor; NTRK3; Ntrk3_tv3; TrkC; trk-C; trkC tyrosine kinase; tyrosine kinase receptor; tyrosine kinase receptor C
Nombre común TrkC
Símbolo de gen Ntrk3
Familia Quinasa Neurotrophic Receptor (NTRK) Kinase Family
Longitud de la proteína 510-825
Tipo de producto Protein
Conjugado Unconjugated
Especie Human
Recombinante Recombinant
Etiqueta de proteína His-tag
Secuencia 510-825
Contenido y almacenamiento -80°C, Avoid Freeze/Thaw Cycles
Entrada del ensayo Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity
Grupo de cinasas Tyrosine Kinases
Condiciones de envío Dry Ice
Compatibilidad de sistemas LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™
Entrada diana NTRK3
Gen diana neurotrophic tyrosine kinase, receptor, type 3
Sistema de expresión Baculovirus
Familia de proteínas Kinases & Inhibitors
Forma de proteína Recombinant, Catalytic Domain, Cytoplasmic
Formulario Liquid
Subtipo de proteína Receptor Tyrosine Kinases
Categoría de investigación Signal Transduction
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