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Invitrogen™ Human MARK1 (MARK), GST Tag Recombinant Protein

Código de producto. 11535026
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Cantidad:
10 μg
Tamaño de la unidad:
10 microgramos
Código de producto. Cantidad unitSize
11535026 10 μg 10 microgramos
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Código de producto. 11535026

Marca: Invitrogen™ PV4395

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Descripción

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length

MARK1 (MARK) is a serine/threonine kinase which is involved in cytoskeletal organization and biogenesis. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. MARK1 is involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso Q9P0L2
Concentración See Label
Para utilizar con (aplicación) Kinase Assay
Formulación 50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5
ID de gen (Entrez) 4139
Peso molecular 116.5 kDa
Nombre Human MARK1 (MARK), GST Tag
Cantidad 10 μg
Estado normativo For research use only. Not for use in diagnostic procedures
Alias de gen AW491150; B930025N23Rik; ELKL motif serine/threonine-protein kinase 3; ELKL motif serine-threonine protein kinase 3; Emk3; KIAA1477; MAP/microtubule affinity regulating kinase 1; MAP/microtubule affinity-regulating kinase 1; MARK; MARK1; mark1 {ECO:0000312; microtubule affinity regulating kinase 1; mKIAA1477; mPar-1 c; PAR1 homolog c; Par1c; Par-1 c; RGD:619882}; serine/threonine-protein kinase MARK1
Nombre común MARK1
Familia Quinasa CAMKL
Tipo de producto MARK1 (MARK) Recombinant Human Protein
Conjugado Unconjugated
Especie Human
Recombinante Recombinant
Etiqueta de proteína GST-tag
Secuencia Full length
Contenido y almacenamiento -80°C, Avoid Freeze/Thaw Cycles
Sistema de expresión Baculovirus
Familia de proteínas Kinase and inhibitors
Formulario Liquid
Subtipo de proteína Serine/threonine kinase
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