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Invitrogen™ Human MAPK8 (JNK1), His Tag Recombinant Protein

Código de producto. 15418453
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Cantidad:
100 μg
10 μg
1 mg
Tamaño de la unidad:
1 miligramo
10 microgramos
100 microgramos
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Código de producto. Cantidad unitSize
15418453 100 μg 100 microgramos
11583427 10 μg 10 microgramos
10053082 1 mg 1 miligramo
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Código de producto. 15418453 Proveedor Invitrogen™ N.º de proveedor PR5340A
 Artículo restringido
Fecha estimada de envoi: 10-08-2026
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Descripción

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

MAPK8 (JNK1) is activated by the presence of misfolded proteins in the endoplasmic reticulum. It is also a crucial mediator of insulin resistance and obesity. It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso P45983
Concentración See Label
Para utilizar con (aplicación) Kinase Assay
Formulación 50mM tris with 0.05% Triton X-100, 150mM NaCl, 2mM DTT, 0.05mM EDTA, 50% glycerol and no preservative; pH 7.5
ID de gen (Entrez) 5599
Peso molecular 47.6 kDa
Nombre Human MAPK8 (JNK1), His Tag
Intervalo de pH 7.5
Método de purificación Purified
Cantidad 100 μg
Requisitos de almacenamiento -80°C, Avoid Freeze/Thaw Cycles
Estado normativo RUO
Alias de gen AI849689; c-Jun N-terminal kinase 1; FLJ12099; FLJ33785; JNK; JNK1; JNK1 beta1 protein kinase; jnk1a-1; JNK1A2; JNK21B1/2; JNK-46; JUN N-terminal kinase; MAP kinase 8; MAPK 8; Mapk8; mapk8 protein; mapk8b; MGC50974; mitogen activated protein kinase 8; mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 8b; OTTHUMP00000019552; p493F12; p54 gamma; p54bSAPK; PRKM8; protein kinase JNK1; protein kinase mitogen-activated 8; SAPK gamma; SAPK1; SAPK1C; stress-activated protein kinase 1; stress-activated protein kinase 1c; Stress-activated protein kinase JNK1; zgc:112379
Nombre común JNK1
Símbolo de gen MAPK8
Familia Quinasa MAP Kinase Family
Tipo de producto Protein
Conjugado Unconjugated
Especie Human
Recombinante Recombinant
Etiqueta de proteína His-tag
Secuencia Full length
Contenido y almacenamiento -80°C, Avoid Freeze/Thaw Cycles
Grupo de cinasas Ser⁄Thr Kinases: CMGC Group
Condiciones de envío Dry Ice
Sistema de expresión Insect cells
Familia de proteínas Kinases & Inhibitors
Forma de proteína Recombinant, Full Length
Formulario Liquid
Categoría de investigación Neurology, Oncology
Grado de pureza o calidad 95% by SDS-PAGE
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