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LJI308, MedChemExpress

Código de producto. 16467858
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Código de producto. Cantidad unitSize
16467858 10 mg 10 miligramos
16463676 25 mg 25 miligramos
16447676 100 mg 100 miligramos
16443807 50 mg 50 miligramos
16400328 5 mg 5 miligramos
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Product Code. 16467858 Supplier Medchem Express Supplier No. HY19713

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Description

MedChemExpress LJI308 is a potent pan-ribosomal S6 kinase (RSK) inhibitor, with IC50s of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. LJI308 inhibits the phosphorylation of RSK (T359/S363) and YB-1 (S102) after irradiation, treatment with EGF, and in cells expressing a KRAS mutation.

LJI308 is a potent pan-ribosomal S6 kinase (RSK) inhibitor, with IC50s of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. LJI308 inhibits the phosphorylation of RSK (T359/S363) and YB-1 (S102) after irradiation, treatment with EGF, and in cells expressing a KRAS mutation.

Specifications

Nombre del producto químico o material LJI308
CAS 1627709-94-7
Color Light Yellow
Notas de grado de pureza Research
Fórmula molecular C21H18F2N2O2
Cantidad 10 mg
Información de solubilidad DMSO : 25 mg/mL (67.86 mM; Need ultrasonic)
SMILES OC1=C(F)C=C(C2=C(C3=CC=C(N4CCOCC4)C=C3)C=CN=C2)C=C1F
Peso molecular (g/mol) 368.38
Formula Weight (peso de la fórmula) 368.38
Porcentaje de pureza 99.21%
Grado Research
Forma física Solid
Para utilizar con (aplicación) Cancer-Kinase/protease
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Research purposes only

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