Invitrogen™ Human TNF-beta Recombinant Protein

Descripción

RP-75741 contains purified recombinant human TNF beta protein with an N-terminal hexahistidine tag. RP-75741 may be used as a positive control in many immunological assays.

TNF beta, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis.