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Invitrogen™ Human TCP-1 zeta (aa 493-530) Control Fragment Recombinant Protein

Código de producto. 30200159
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
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30200159 100 μL 100 microlitros
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Código de producto. 30200159 Proveedor Invitrogen™ N.º de proveedor RP104349

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Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60193 (PA5-60193. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The protein TCP-1 (t complex polypeptide 1) is a subunit of the heterooligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species, TCP-1 alpha, beta, gamma, delta, epsilon, zeta, eta and theta, each encoded by a different gene. Two zeta subunits have been described: TCP-1 zeta (also designated TCP-1 zeta1) and TCP-1 zeta2. TCP-1 subunits are proposed to have independent functions in folding its in vivo substrates, the actins and tubulins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecular chaperone for Actin and Tubulin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso P40227
Concentración ≥5.0 mg/mL
Para utilizar con (aplicación) Blocking Assay, Control
Formulación 1 M urea, PBS with no preservative; pH 7.4
ID de gen (Entrez) 908
Nombre Human TCP-1 zeta (aa 493-530) Control Fragment
Cantidad 100 μL
Estado normativo RUO
Alias de gen acute morphine dependence related protein 2; acute morphine dependence-related protein 2; amino acid transport defect-complementing; CCT zeta1; CCT- zeta1; CCT- zeta-1; CCT zeta-1; Cct6; Cct6a; Cctz; Cctz1; Cctz-1; CCT-zeta; CCT-zeta-1; chaperonin containing T-complex subunit 6; chaperonin containing TCP-1; chaperonin containing TCP1 subunit 6 A; chaperonin containing Tcp1, subunit 6 A (zeta 1); chaperonin containing Tcp1, subunit 6 A (zeta); chaperonin subunit 6 A (zeta); histidine transp; histidine transport regulator 3; HTR3; MoDP-2; T-complex protein 1 subunit zeta; T-complex protein 1, zeta subunit; TCP 1 zeta; TCP1 zeta; TCP-1- zeta; TCP1- zeta; TCP-1-zeta; Tcp20; TCPZ; TTCP20
Nombre común TCP-1 zeta
Símbolo de gen CCT6A
Conjugado Unconjugated
Especie Human
Recombinante Recombinant
Etiqueta de proteína His-ABP-tag
Secuencia GVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Sistema de expresión E. coli
Formulario Liquid
Grado de pureza o calidad >80% by SDS-PAGE and Coomassie blue staining
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